Systemic Interplay of BDNF and Serotonin Pathways Defines Behavioral and Molecular Responses to Midbrain 5-HT7 Overexpression and Chronic Ethanol Consumption.
📄 Abstract
Chronic ethanol exposure and genetic factors interact to drive neuroadaptations in alcohol use disorders (AUD). However, the system-level coordination of molecular responses across brain regions remains unclear. The 5-HT system and BDNF are key regulators of neuroplasticity in alcoholism. The 5-HT
Confidence:
0.08
· 4 полей извлечено
Идентификация (6 полей)
Target
5-HT7 receptor
0.90
Alt. target
5-HT7R
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Protein family
G protein-coupled receptor
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Functional class
serotonin receptor
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Механизм действия (21 полей)
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