Mechanism of Inosine from
📄 Abstract
Gut microbial metabolites play a crucial role in modulating cognitive function. In a previous animal study, oral administration of
Confidence:
0.11
· 5 полей извлечено
Идентификация (6 полей)
Механизм действия (21 полей)
Mechanism
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Mutations (obesity/lean)
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Activity (obesity)
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Activity temporal
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Energy balance
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Appetite
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Fat metabolism
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Lipolysis
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Thermogenesis
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Muscle metabolism
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Inflammation
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Glucose metabolism
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AA metabolism
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Hormonal pathways
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Cell death
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Adipocyte fibrosis
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Upstream (biochem)
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Upstream (physiol)
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Downstream (biochem)
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Downstream (physiol)
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PTMs
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Экспрессия (8 полей)
Tissue expression
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In vitro
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In vivo
In-vivo and in-vitro nutrient-gene interactions
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In silico
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Genetic association
Association studies of gene variants and response to dietary challenges
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Ex vivo
ex vivo immunological function
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Animal model
rat, mouse
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Diet/model
high-fructose diet, omega-3 fatty acid-treated
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Клиника (11 полей)
Drug
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Indication
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Patient subgroups
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Safety concerns
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Off-target
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Trial stage
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Pharma competitors
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AE severity
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MOA weight loss
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Endpoints
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Approved
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