From wild plant to functional ingredient: phytochemical insights and neuroprotective activity of
Confidence:
0.11
· 5 полей извлечено
Идентификация (6 полей)
Механизм действия (21 полей)
Mechanism
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0.00
Mutations (obesity/lean)
gain-of-function mutation in adenylate cyclase 3
0.90
Activity (obesity)
protects from diet-induced obesity
0.90
Activity temporal
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0.00
Energy balance
affects metabolic response to high-fat diet
0.80
Appetite
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0.00
Fat metabolism
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0.00
Lipolysis
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0.00
Thermogenesis
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0.00
Muscle metabolism
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0.00
Inflammation
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0.00
Glucose metabolism
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0.00
AA metabolism
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0.00
Hormonal pathways
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0.00
Cell death
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0.00
Adipocyte fibrosis
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0.00
Upstream (biochem)
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0.00
Upstream (physiol)
—
0.00
Downstream (biochem)
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0.00
Downstream (physiol)
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0.00
PTMs
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0.00
Экспрессия (8 полей)
Tissue expression
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0.00
In vitro
In vitro studies to investigate the potential neuroprotective and neurotransmitter modulation effects of a standardized Ginkgo biloba extract associated with phosphatidylserine.
0.90
In vivo
—
0.00
In silico
Bioinformatics and Deep Learning Approach to Discover Food-Derived Active Ingredients for Alzheimer's Disease Therapy; Cholinergic Inhibition and Antioxidant Potential of Gongronema latifolium Benth Leaf in Neurodegeneration: Experimental and In Silico Study; In Silico Profiling of Phytochemicals for Modulating Amyloid Beta-Mediated Immune Regulation and Neuroinflammation in Alzheimer's Disease.
0.90
Genetic association
—
0.00
Ex vivo
—
0.00
Animal model
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0.00
Diet/model
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0.00
Клиника (11 полей)
Drug
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0.00
Indication
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0.00
Patient subgroups
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0.00
Safety concerns
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0.00
Off-target
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0.00
Trial stage
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0.00
Pharma competitors
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0.00
AE severity
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0.00
MOA weight loss
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0.00
Endpoints
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0.00
Approved
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0.00