Repetitive Magnetic Stimulation Modulates the Gene Expression of Neurotrophins and their Receptors in Neuroblastoma Cells.
📄 Abstract
Repetitive magnetic stimulation (rMS) is used to treat neurological conditions. Understanding its modulatory effects requires investigating cellular processes and molecular pathways Active (75-, 150-, and 300-sec exposure) or sham rMS was administered daily (4 days/300mT-1Hz) to two neuronal [SK-N-BE(2) and SH-SY5Y] and one non-neuronal (HOS) tumor line. Cell viability, cell death, and gene expression of Both neuroblastoma cell lines, SH-SY5Y (150-sec) and SK-N-BE(2) (75-sec), exhibited increased viability compared to the 300-sec group immediately after treatment; however, none of the stimulated groups was different from sham. rMS increased rMS did not affect cell viability or death in these
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Идентификация (6 полей)
Механизм действия (21 полей)
Mechanism
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Экспрессия (8 полей)
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SK-N-BE(2), SH-SY5Y, HOS
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Клиника (11 полей)
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