Influence of BDNF rs10835210 on right parahippocampal volume and its related cognitive function in first- and multiple-episode bipolar disorder.
📄 Abstract
The brain-derived neurotrophic factor ( A total of 43 first-episode mania patients (FEM), 110 multiple-episode mania patients (MEM) and 80 healthy controls were enrolled in our study. We investigated the impact of We found a significant interaction between This is the first study to demonstrate that The online version contains supplementary material available at 10.1186/s12888-026-07949-7.
Confidence:
0.13
· 5 полей извлечено
Идентификация (6 полей)
Target
BDNF
1.00
Alt. target
brain-derived neurotrophic factor
1.00
Protein family
neurotrophin
0.90
Functional class
growth factor
0.90
Subcellular loc.
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0.00
Isoforms (metab/obesity)
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0.00
Механизм действия (21 полей)
Mechanism
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Mutations (obesity/lean)
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Activity (obesity)
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Activity temporal
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Energy balance
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Appetite
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Fat metabolism
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Lipolysis
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Thermogenesis
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Muscle metabolism
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Inflammation
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Glucose metabolism
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AA metabolism
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Hormonal pathways
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Cell death
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Adipocyte fibrosis
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Upstream (biochem)
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Upstream (physiol)
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Downstream (biochem)
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Downstream (physiol)
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PTMs
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Экспрессия (8 полей)
Tissue expression
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In vitro
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In vivo
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In silico
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Genetic association
BDNF rs10835210
0.90
Ex vivo
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0.00
Animal model
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Diet/model
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0.00