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Извлечено: 997 / 997 (100.0%) Средняя confidence: 0.13
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A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.

PMID: 41815853 · DOI: 10.25122/jml-2025-0172 · Journal of medicine and life, 2026 · Rogene Eichler West, Anima Biswas, Rahul Rao, Himanshu Tayade, John Ademola
📄 Abstract

Stress and anxiety are interconnected, sharing both behavioural and neural foundations. Ashwagandha (

Confidence: 0.08 · 5 полей извлечено
Идентификация (6 полей)
Target
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Alt. target
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Protein family
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Functional class
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Subcellular loc.
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Isoforms (metab/obesity)
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Механизм действия (21 полей)
Mechanism
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Mutations (obesity/lean)
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Activity (obesity)
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Activity temporal
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Energy balance
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Appetite
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Fat metabolism
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Lipolysis
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Thermogenesis
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Muscle metabolism
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Inflammation
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Glucose metabolism
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AA metabolism
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Hormonal pathways
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Cell death
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Adipocyte fibrosis
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Upstream (biochem)
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Upstream (physiol)
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Downstream (biochem)
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Downstream (physiol)
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PTMs
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Экспрессия (8 полей)
Tissue expression
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In vitro
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In vivo
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In silico
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Genetic association
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Ex vivo
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Animal model
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Diet/model
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Клиника (11 полей)
Drug
ashwagandha
0.90
Indication
stress and anxiety
0.90
Patient subgroups
healthy adults
0.80
Safety concerns
0.00
Off-target
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Trial stage
Phase 3
0.70
Pharma competitors
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AE severity
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MOA weight loss
0.00
Endpoints
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Approved
False
0.50