Blood biomarker changes and relationships after low dose oral ketamine treatment for post-traumatic stress disorder (PTSD).
Confidence:
0.12
· 5 полей извлечено
Идентификация (6 полей)
Механизм действия (21 полей)
Mechanism
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Mutations (obesity/lean)
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Activity (obesity)
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Activity temporal
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Energy balance
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0.00
Appetite
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0.00
Fat metabolism
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0.00
Lipolysis
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0.00
Thermogenesis
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0.00
Muscle metabolism
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0.00
Inflammation
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0.00
Glucose metabolism
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AA metabolism
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Hormonal pathways
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Cell death
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Adipocyte fibrosis
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Upstream (biochem)
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Upstream (physiol)
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0.00
Downstream (biochem)
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0.00
Downstream (physiol)
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0.00
PTMs
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Экспрессия (8 полей)
Tissue expression
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In vitro
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In vivo
Oral administration of MCT oil reduces anxiety-like behavior and is associated with differences in serum BDNF responses in a rat model of PTSD; Impact of subanesthetic ketamine delivered via AmyloLipid nanovesicle (ALN)-based intranasal system on biobehavioral responses in an animal model of PTSD
0.90
In silico
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Genetic association
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Ex vivo
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Animal model
rat model of PTSD
0.90
Diet/model
MCT oil
0.90
Клиника (11 полей)
Drug
ketamine
0.95
Indication
post-traumatic stress disorder (PTSD)
0.95
Patient subgroups
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0.00
Safety concerns
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0.00
Off-target
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0.00
Trial stage
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0.00
Pharma competitors
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AE severity
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MOA weight loss
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Endpoints
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Approved
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