Commentary for "Longitudinal implications of BDNF rs6265 polymorphism on motor and non-motor features of Parkinson's disease in Korean population".
Confidence:
0.11
· 4 полей извлечено
Идентификация (6 полей)
Target
BDNF
1.00
Alt. target
Brain-derived neurotrophic factor
1.00
Protein family
—
0.00
Functional class
—
0.00
Subcellular loc.
—
0.00
Isoforms (metab/obesity)
—
0.00
Механизм действия (21 полей)
Mechanism
—
0.00
Mutations (obesity/lean)
BDNF rs6265
0.90
Activity (obesity)
—
0.00
Activity temporal
—
0.00
Energy balance
—
0.00
Appetite
—
0.00
Fat metabolism
—
0.00
Lipolysis
—
0.00
Thermogenesis
—
0.00
Muscle metabolism
—
0.00
Inflammation
—
0.00
Glucose metabolism
—
0.00
AA metabolism
—
0.00
Hormonal pathways
—
0.00
Cell death
—
0.00
Adipocyte fibrosis
—
0.00
Upstream (biochem)
—
0.00
Upstream (physiol)
—
0.00
Downstream (biochem)
—
0.00
Downstream (physiol)
—
0.00
PTMs
—
0.00
Экспрессия (8 полей)
Tissue expression
—
0.00
In vitro
—
0.00
In vivo
—
0.00
In silico
—
0.00
Genetic association
BDNF rs6265 polymorphism associated with motor and non-motor features of Parkinson's disease; BDNF Val66Met polymorphism associated with phenoconversion in isolated REM sleep behavior disorder; BDNF Val66Met polymorphism associated with anxiety-related disorders
0.90
Ex vivo
—
0.00
Animal model
—
0.00
Diet/model
—
0.00