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Hypothalamic thermoregulatory neurons divergently modulate isoflurane anesthesia via temperature dependent and independent mechanisms.

PMID: 42004037 · DOI: 10.1016/j.isci.2026.115542 · iScience, 2026 · Shuang Cai, Wen Z Yang, Mao Xu, Huimin Chen, Liang Zhou, Tianyuan Luo, Shouyang Yu, Kan Zhang, Haiying Wang, Tian Yu, Ji
📄 Abstract

Perioperative hypothermia is common clinically. The neural mechanisms underlying general anesthesia and the hypothermia it induces remain elusive. We found that lower core temperature (T

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Идентификация (6 полей)
Механизм действия (21 полей)
Экспрессия (8 полей)
Клиника (11 полей)