Corrigendum to "AdipoRon ameliorates anxiety- and depression-like behaviors in chronic restraint-stressed mice via AMPK-PPARα-BDNF-TrkB signaling" [Eur. J. Pharmacol. (2026) 1011 178468 doi: 10.1016/j.ejphar.2025.178468].
Confidence:
0.09
· 4 полей извлечено
Идентификация (6 полей)
Механизм действия (21 полей)
Mechanism
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0.00
Mutations (obesity/lean)
Mutation in Adcy3 (Adenylate cyclase 3) increases adiposity
0.90
Activity (obesity)
—
0.00
Activity temporal
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0.00
Energy balance
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0.00
Appetite
—
0.00
Fat metabolism
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0.00
Lipolysis
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0.00
Thermogenesis
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0.00
Muscle metabolism
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0.00
Inflammation
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0.00
Glucose metabolism
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0.00
AA metabolism
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0.00
Hormonal pathways
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0.00
Cell death
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0.00
Adipocyte fibrosis
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0.00
Upstream (biochem)
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0.00
Upstream (physiol)
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0.00
Downstream (biochem)
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0.00
Downstream (physiol)
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0.00
PTMs
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0.00
Экспрессия (8 полей)
Tissue expression
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0.00
In vitro
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0.00
In vivo
AdipoRon ameliorates anxiety- and depression-like behaviors in chronic restraint-stressed mice; AICAR improves depression-like behaviors in a microbiota disruption model; 7,8-Dihydroxyflavone ameliorates depression-like behaviors in mice induced by Toxoplasma gondii
0.90
In silico
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0.00
Genetic association
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0.00
Ex vivo
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0.00
Animal model
chronic restraint-stressed mice; microbiota disruption model; Toxoplasma gondii-induced mice
0.90
Diet/model
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0.00
Клиника (11 полей)
Drug
AdipoRon
0.90
Indication
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0.00
Patient subgroups
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0.00
Safety concerns
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0.00
Off-target
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0.00
Trial stage
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0.00
Pharma competitors
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0.00
AE severity
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0.00
MOA weight loss
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0.00
Endpoints
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0.00
Approved
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0.00