Selenium-containing peptides attenuating Pb-induced memory impairment through microRNA-mediated signaling.
📄 Abstract
Lead (Pb) accumulation in the hippocampus and the resulting oxidative stress contribute to memory impairments, highlighting the hippocampus as a primary target for Pb neurotoxicity. Selenium-containing peptides TSeMMM and SeMDPGQQ are able to alleviate Pb-induced oxidative neurological damage and the specific microRNAs involved in the memory protection by the two peptides need to be explored. In this study, mouse memory impairment models were constructed through the administration of 20 mg kg
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Идентификация (6 полей)
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mouse memory impairment models constructed through administration of 20 mg kg
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