Application of Treatment Response Biomarkers from Major Depression to Perinatal Depression.
Confidence:
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Идентификация (6 полей)
Target
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Alt. target
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Protein family
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Functional class
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Subcellular loc.
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Isoforms (metab/obesity)
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Механизм действия (21 полей)
Mechanism
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Mutations (obesity/lean)
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Activity (obesity)
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Activity temporal
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Energy balance
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Appetite
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Fat metabolism
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Lipolysis
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Thermogenesis
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Muscle metabolism
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Inflammation
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Glucose metabolism
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AA metabolism
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Hormonal pathways
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Cell death
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Adipocyte fibrosis
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Upstream (biochem)
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Upstream (physiol)
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Downstream (biochem)
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Downstream (physiol)
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PTMs
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Экспрессия (8 полей)
Tissue expression
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In vitro
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In vivo
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In silico
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Genetic association
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Ex vivo
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Animal model
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Diet/model
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Клиника (11 полей)
Drug
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Indication
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Patient subgroups
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Safety concerns
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Off-target
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Trial stage
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Pharma competitors
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AE severity
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MOA weight loss
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Endpoints
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Approved
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